Vitamin D

Assorted links

1. The Voluntary Human Extinction Movement (so much self-loathing, it's hard to read)

2. Skinning a deer with obsidian (not gross, but they are skinning a deer)

3. Vitamin D deficiency and the benefits of sun exposure (finally getting some mainstream recognition)

4. Devastatingly even-handed criticism of the China Study, the vegetarian/vegan holy book, courtesy of Dr. Michael Eades

Gwyneth Paltrow has osteopenia, needs more sun

Gwyneth Paltrow has brittle bones -- and needs more sun.

In her newsletter, she recently told the story of fracturing her leg, going to doctors, and being diagnosed with osteopenia, a precursor to osteoperosis. Her doctors said her Vitamin D levels were "the lowest they had ever seen". Gwyneth's reaction to being told to get more sun? Much like anyone else's who has heard scary headline after scary headline on the dangers of sun exposure: "I was curious if this was safe, having been told for years to stay away from its dangerous rays, not to mention a tad bit confused."

She includes an essay which is one of the clearest articulations I've read on the benefits of Vitamin D and sensible sun exposure. Read the whole thing here.

Via Hyperlipid and Celebitchy.

Media hysteria on tanning beds and melanoma

A recent study on tanning beds and melanoma has been making the rounds: "Indoor Tanning and Risk of Melanoma: A Case-Control Study in a Highly Exposed Population". The WSJ, Time, NPR, and USA Today have all covered it. The big statistic that everyone is throwing around is that "people who tanned indoors had a 74% higher chance of developing melanoma than those who hadn’t." Note that the reason this paper is such a big deal is because there has never been strong evidence that using tanning beds caused melanoma.

Well, I had the great pleasure of meeting Dr. Michael Holick today, and we discussed this very paper. You can view the full text here. Let's go the actual science and see what it says.

The 74% number comes from Table 3, second row, in the last column called multivariate adjusted OR (odds ratio). You'll see a 1.74 (hence, 74% more likely), plus a confidence interval. (This interval, or error bounds, simply indicates that if you ran this experiment 100 times, 95% of the time you'd expect this value to fall between 1.42 and 2.14.) The odds ratio for hours spent in a tanning bed increases to 3.18 (218% more likely) with duration of tanning bed use.

Well, from all the media hysteria, you'd expect that tanning beds would be the primary risk factor uncovered in the study. And you'd be wrong. Flip up to Table 2 and let's take a look at the odds ratios of other factors.

Hair Color

What color is your hair? Redheads have an OR of 3.53 -- which means red heads are 253% more likely to get melanoma. Compare that to the 74% number associated with ever having gone to the tanning salon. And even blondes are 117% more likely (2.17 OR). Having blonde hair or red hair has more to do with your risk of melanoma than whether you've ever gone to the tanning salon.

Skin Color

Having very fair skin increases your chances of melanoma by a whopping 450% (5.50 OR). Fair skin is 263% more likely, and even light olive skin is more important than having gone to the tanning salon.

Moles

Moles!!! If you have a bunch of moles you're 1,281% more likely to get melanoma. Having lots of moles is nearly 20X more important than whether you've gone to a tanning salon.

Lifetime Sun Exposure

Three measure of sun exposure show that high lifetime sun exposure decreases risk of melanoma (ORs of .85, .95, and .84).

Sun Burns

Sun burns, on the other hand, do increase your risk of melanoma, comparable to tanning salon usage.

Mean Lifetime Sunscreen Use

Get this -- THE SAME STUDY THAT CONNECTS TANNING BEDS WITH MELANOMA ALSO CONCLUDES THAT HIGHER SUNSCREEN USAGE INCREASES YOUR RISK OF MELANOMA. Medium or High mean lifetime sunscreen usage increases your chances of getting melanoma by about 30%. But somehow "Sunscreen usage causes melanoma" is a less catchy headline than "Tanning beds cause melanoma".

My point is not that there are no risks to tanning beds. My point is that the biggest risk factors for melanoma are NOT tanning bed usage and are NOT sun exposure. It's having moles. And red hair or blonde hair. And fair skin.

So how about we do some science that actually tries to understand what's going on, instead of attention-grabbing headlines that confuse and scare people.

Assorted links

1. Another benchmark in Craig Venter's quest to create life.

The pros: "I think they're going to potentially create a new industrial revolution," [Venter] said. "If we can really get cells to do the production that we want, they could help wean us off oil and reverse some of the damage to the environment by capturing carbon dioxide."

The cons: "We don't know how these organisms will behave in the environment." [Dr. Helen Wallace of Genewatch]

2. Michael Holick interview with the New York Times (a few months old)

"The American Academy of Dermatology still has that recommendation that you should never be exposed to one ray of direct sunlight without sun protection."

3. Michael Pollan's The Food Movement, Rising in the New York Review of Books

On the different parts of the food movement:

"Among the many threads of advocacy that can be lumped together under that rubric we can include school lunch reform; the campaign for animal rights and welfare; the campaign against genetically modified crops; the rise of organic and locally produced food; efforts to combat obesity and type 2 diabetes; “food sovereignty” (the principle that nations should be allowed to decide their agricultural policies rather than submit to free trade regimes); farm bill reform; food safety regulation; farmland preservation; student organizing around food issues on campus; efforts to promote urban agriculture and ensure that communities have access to healthy food; initiatives to create gardens and cooking classes in schools; farm worker rights; nutrition labeling; feedlot pollution; and the various efforts to regulate food ingredients and marketing, especially to kids.

It’s a big, lumpy tent..."

On libertarians and evangelicals:

In his 2006 book Crunchy Cons, Rod Dreher identifies a strain of libertarian conservatism, often evangelical, that regards fast food as anathema to family values, and has seized on local food as a kind of culinary counterpart to home schooling.

And more on traditionalism:

In a challenge to second-wave feminists who urged women to get out of the kitchen, Flammang suggests that by denigrating “foodwork”—everything involved in putting meals on the family table—we have unthinkingly wrecked one of the nurseries of democracy: the family meal."

(Much the rest is familiar if you've read Pollan before and doesn't bear on the excerpts above.)

Why I went to the tanning salon this winter

Part of paleo is about experimentation and discovery. This winter I started experimenting with going to the solarium....better known as the tanning salon. That's right, I went to the tanning salon. Really courting medical controversy here. So here's why I went.

My initial reason was to get a base layer and avoid a sunburn in Mexico. I had signed up for the MovNat course in Mexico in mid-January, and it seemed prudent to get a base layer to make it less likely I would burn in Mexico. Sun burns are what cause the most damage to your skin and most increase your chances of skin cancer. My sessions were purposefully short duration (<7 minutes) and low intensity, and so I needed to do a few of them before I got a noticeable tan.

Healthy Vitamin D levels decrease your overall chances of getting cancer. My reading of the literature indicated that 1) it's extremely difficult to get sufficient Vitamin D from food and even supplements, 2) the deadly forms of skin cancer are more rare than generally thought, 3) they don't seem connected to sun exposure per se (sun burns are the more likely culprit), and 4) and your higher chances of getting skin cancer are far outweighed by the cancers you avoid by getting enough Vitamin D. Use of a tanning bed -- with the right UV frequencies -- has also been shown to increase Vitamin D levels. As for a few more wrinkles as I get older, that seems to be true, but I just don't care. For an excellent overview of what we know about the sun, Vitamin D, and cancer, watch this video by Dr. Michael Holick at BU. (He doesn't endorse tanning.)

My mood improved immediately. I don't know what to say, it just did away with the winter doldrums. The first time I went was in early January in New York City.

Now, would it better to get moderate sun exposure? Yes. Would it be better to have a UV solution in winter that mimicked natural sun light? Yes. Is it a good idea to go to the tanning salon to get burnt to a crisp in 10 minutes? No, of course not.

Who could benefit most from going to the solarium? People with dark skin. Dark-skinned people are adapted for an equatorial environment with enormously high sun exposure all year round. It's as if they are wearing high SPF skin block all the time. They need more sun to generate the same amount of Vitamin D as a fair-skinner person. So black people who live in high latitudes or who live near the equator but are covered up all the time are particularly at risk. Bad news for burqas -- blocking out the sun is causing rickets and osteoporosis in Middle Eastern women. From the abstract:

"Despite ample sunshine, the Middle East (15°-36°N) and Africa (35°S-37°N), register the highest rates of rickets worldwide. This is in large part explained by limited sun exposure due to cultural practices and prolonged breast feeding without vitamin D supplementation in the Middle East, and by dark skin colour and calcium deficiency, rather than vitamin D deficiency, in several countries in Africa. Both regions also have a high prevalence for hypovitaminosis D, the latency disease for osteoporosis, and the main focus of this discussion."

Wouldn't it be ironic if the first tax enacted as part of the health care plan was actually counter-productive? I'd be willing to wager that the 10% tax on tanning salons caused a net decrease in the health of African-Americans. (Not sure how many actually go.)

Anyhow, here's to a little experimentation. I'm sure I'll have a few more posts on this taboo subject in the days to come.